A catalytic multicomponent coupling reaction for the enantioselective synthesis of spiroacetals
作者： Félix Rodríguez , Lara Cala , Abraham Mendoza , Francisco J. Fañanás
DOI: 10.1039/C3CC00118K
关键词:
摘要: The first multicomponent catalytic asymmetric synthesis of spiroacetals has been described. Hybrid molecules comprising a spiroacetal scaffold (a natural-product inspired scaffold) and an α-amino acid motif privileged fragment) are easily available through gold phosphate-catalysed one-pot three component coupling reaction alkynols, anilines glyoxylic acid.
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