A Scientific Review of Age Determination for a Laboratory Rat: How Old is it in Comparison with Human Age?

摘要: Laboratory rats are among the most commonly used experimental animals, offering best functionally characterized model mammalian system. The rat serves as a organism for analysis of number important biomedical traits, including toxicology. In many instances, while individuals engaged in research calculating doses an experiment or relating health effect certain drug chemical to  human, questions arise such ‘how old is people years?' ‘is newborn good human?'. Some reviews have tried answer these various ways. This review attempts using different approach, and shows that rat-human age correlations differ markedly at stages life development. metaphorically illustrates correlation their periods, from weaning (where 42.4 days resemble human year) aged phase 17.1 equal year).