The Association between Hypoxia-Inducible Factor-1 α Gene C1772T Polymorphism and Cancer Risk: A Meta-Analysis of 37 Case-Control Studies
作者： Pengfei He , Qi Han , Jiajia Liu , Dongjuan Liu , Xin Zhao
DOI: 10.1371/JOURNAL.PONE.0083441
关键词:
摘要: Purpose Hypoxia-inducible factor-1 (HIF-1) is a key transcription factor that regulates the cellular adaptation to hypoxia. HIF-1α gene single nucleotide polymorphisms (SNPs) are implicated be associated with cancer risks. However, results from published studies remained inconclusive. The aim of this study investigate relationship G1790A polymorphism using meta-analysis.
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