Ototoxicity of Ethacrynic Acid and Aminoglycoside Antibiotics in Uremia
作者： Robert H. Mathog , William J. Klein
DOI: 10.1056/NEJM196905292802208
关键词:
摘要: THE ototoxic effects of aminoglycosides such as streptomycin, kanamycin and neomycin are well established. Since renal failure increases the hazard ototoxicity from these drugs, it can be expected that, in presence azotemia delayed drug excretion, other agents thought to minimally may exhibit an enhanced capacity for this adverse effect.1 Before report Schneider Becker2 ethacrynic acid was not considered drug. They described induction acute transient hearing loss by five patients with marked impairment function. Others3 4 5 6 have alluded single cases similar effects. . . .
sci-hub.se 参考文章(8)
GREGORY J. MATZ, T. H. WALLACE, PAUL H. WARD, The ototoxicity of kanamycin: A comparative histopathological study Laryngoscope. ,vol. 75, pp. 1690- 1698 ,(1965) , 10.1288/00005537-196511000-00002
Calvin M. Kunin, ABSORPTION, DISTRIBUTION, EXCRETION AND FATE OF KANAMYCIN Annals of the New York Academy of Sciences. ,vol. 132, pp. 811- 818 ,(1966) , 10.1111/J.1749-6632.1966.TB42999.X
VeerasamyK.G. Pillay, FranklinD. Schwartz, Kenji Aimi, RobertM. Kark, Transient and permanent deafness following treatment with ethacrynic acid in renal failure. The Lancet. ,vol. 293, pp. 77- 79 ,(1969) , 10.1016/S0140-6736(69)91092-7
Gregory J. Matz, Ototoxic Drugs and Poor Renal Function JAMA: The Journal of the American Medical Association. ,vol. 206, pp. 2119- 2119 ,(1968) , 10.1001/JAMA.1968.03150090195037
Sydney M. Finegold, TOXICITY OF KANAMYCIN IN ADULTS Annals of the New York Academy of Sciences. ,vol. 132, pp. 942- 956 ,(1966) , 10.1111/J.1749-6632.1966.TB43018.X
George V. Irons, Clinical Experience With Intravenous Administration of Ethacrynic Acid JAMA: The Journal of the American Medical Association. ,vol. 194, pp. 1348- 1351 ,(1965) , 10.1001/JAMA.1965.03090260008002
JOHN F. MAHER, Studies on Ethacrynic Acid in Patients with Refractory Edema Annals of Internal Medicine. ,vol. 62, pp. 15- 29 ,(1965) , 10.7326/0003-4819-62-1-15
R. L. FIELDS, NEOMYCIN OTOTOXICITY. REPORT OF A CASE DUE TO RECTAL AND COLONIC IRRIGATIONS. Archives of Otolaryngology-head & Neck Surgery. ,vol. 79, pp. 67- 70 ,(1964) , 10.1001/ARCHOTOL.1964.00750030071010