The biological importance of ultraviolet light induced DNA-protein crosslinks in Escherichia coli 15 TAU
作者： K.C. Smith , B. Hodgkins , M.E. O'Leary
DOI: 10.1016/0005-2787(66)90248-6
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摘要: Abstract The sensitivity of Escherichia coli 15 TAU to killing by ultraviolet light (2537 A) when grown for various times under several nutritionally restricted conditions (+T−AU; −T+AU; −T−AU) has been measured. Concurrent measurements were made on the amount DNA crosslinked protein these same doses light. There appears be a direct correlation between given dose and intrinsic cells growth studied. These results strongly suggest that crosslinking physiological must play an important role in loss viability irradiated cells.
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