Daptomycin: a new treatment for insidious infections due to gram-positive pathogens.

作者: Philippe Cottagnoud

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摘要: Daptomycin, a new lipopeptide antibiotic, is highly bactericidal against the majority of Gram-positive human pathogens, including methicillin-resistant (MRSA) and vancomycin-resistant enterococci. Its mechanism action unique resulting in destruction membrane potential without lysing cell wall. The daptomycin, its antibacterial spectrum, development resistance pre- clinical studies are discussed this review.

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