Chemotherapy of gastric cancer: a review

摘要: Gastric cancer remains a common malignancy with poor prognosis. Although surgery is possible in 80 to 90% of patients, less than 50% will have resectable disease and most these patients recurrences. Many chemotherapy studies been performed advanced carcinoma the stomach. At least five conventional agents identified as having modest moderate activity. It unclear whether combination more effective terms survival rate. Several new chemotherapeutic are being studied for gastric cancer, but none yet proven be useful drugs. rationale adjuvant well established, substantial number prospective, controlled randomized trials Western countries failed consistently demonstrate benefit. Thus, who remain at high risk recurrence, preferred option entry into carefully planned investigation. In absence research protocol, there no data support routine use an setting stomach cancer.