Effect of sex on vaccination outcomes: important but frequently overlooked.

摘要: It is well established that vaccination does not affect males and females equally. For example, generally mount greater antibody responses to than males, but also suffer more adverse events following vaccination, probably as a result of robust immunity. Despite this, most researchers in the field vaccinology do take biological sex into account when conducting their studies. This omission likely lead loss important information terms both reactogenicity immunogenicity those suffering events. suggests vaccine dose may need be different order achieve same outcome protective immunity while minimising reactogenicity.