作者: You Rong Duan , W.S. Liu , J. Liu , Z.R. Zhang
DOI: 10.4028/WWW.SCIENTIFIC.NET/KEM.288-289.163
关键词:
摘要: The objective of this study was to evaluate the in vivo characteristics poly (ethylene glycol)-poly (lacticacid-co-glycolicacid)-poly (ethylene- glycol) (PELGE) copolymers as drug carriers. In order test circulation time, mitoxantrone (DHAQ) used a model study. DHAQ nanoparticles (DHAQ-NP) were prepared, subsequently DHAQ-NP evaluated by measuring concentration plasma after intravenous administration via tail vein mice. time tested. results showed prolonged residence systemic blood circulation.