Use of reticulocyte cellular indices in the diagnosis and treatment of hematological disorders.

摘要: Automated counting of reticulocytes has markedly increased the precision and accuracy this assay compared with traditional manual counts. In addition, several new reticulocyte parameters are now available to clinicians pathologists. This review examines potential role these in diagnosis management anemias. Reticulocyte maturity can be assessed based on staining intensity reticulocytes, which is proportional their RNA content. However, clinical value numerical estimate immature fraction not been yet demonstrated. bone marrow transplant setting, there no clear evidence that use index results improved care patients, many studies have failed show its superiority white cell count, especially for autologous transplants. Direct measurement volume, hemoglobin concentration, content available. Studies shown parameters, particular, allow a real-time assessment functional state erythroid marrow. setting recombinant human erythropoietin therapy, allows an early detection iron deficiency. Preliminary also may helpful deficiency monitoring replacement therapy.