Proteolytic enzymes, cell surface changes, and viral transformation.

摘要: Publisher Summary This chapter reviews the evidence for and against view that proteolysis plays a role in determining some of phenotypic characteristics virus-transformed cells. It discusses aspects structure cellular membrane surface because one possible mechanism by which proteases might alter cell properties is via selective components. also current knowledge are known to be altered viral transformation there exists at least suggestive involvement proteolytic enzyme. The research into limited enzymes serum, particular plasmin thrombin, virus-induced has only just begun. outline several mechanisms or thrombin system, both, could, surface, produce changes characteristic A large body circumstantial implicating these enzyme systems causing cells recently been obtained. However, critical experiments prove plasmin, other serum modify under usual conditions culture, presence protease inhibitors, remain performed.