Syntheses and Transformations of Sulfinamides

摘要: Sulfinamides, especially enantiopure sulfinamides, are widely used in organic and medicinal synthesis. Syntheses transformations of racemic enantioenriched sulfinamides have achieved great progress. Especially demonstrate interesting valuable reactivity, which deserves to be pertinent. This review summarizes the latest development synthesis transformation will helpful for future related research. 1 Introduction 2 Synthesis Sulfinamides 2.1 Racemic 2.2 Enantiomerically Pure 2.3 Other 3 Transformations 3.1 Condensation with Aldehydes Ketones 3.2 Reaction Alkynes 3.3 Alkenes 3.4 Aryl Alkyl Halides 3.5 Alcohols, Dibenzyl Ether, Benzyl Mercaptan 3.6 tert-Butyldisulfanyl-Substituted Hetarenes 3.7 Asymmetric Sulfides 3.8 N-Phosphino-sulfinamide Ligands 3.9 Asymmetric Synthesis γ-Amino Acids 3.10 Sulfonylation Heterocyclic Compounds 4 Summary Outlook