Fragmentation reactions in the mass spectrometry analysis of neutral oligosaccharides.

摘要: A method is described to obtain multicollision dissociation threshold (MCDT) values. These values provide relative reaction thresholds for in the three major gas-phase fragmentation reactions of oligosaccharides complexed alkali metal ions. The quasimolecular ions are produced using matrix-assisted laser desorption/ionization Fourier transform mass spectrometry. MCDTs ion and glycosidic bond cross-ring cleavages were resolved from kinetic energy dependence collision-induced (CID) products. strengths binding N,N‘-diacetylchitobiose (chitobiose) N,N‘,N‘ ‘-triacetylchitotriose (chitotriose) probed sustained off-resonance irradiation (SORI) CID. Experiments evaluate MCDT obtaining them performed by studying coordinated crown ethers. Molecular dynamic simulations also insight into of...