作者: Jaffer A. Ajani , Susan R. Welch , Martin N. Raber , William S. Fields , Irwin H. Krakoff
DOI: 10.3109/07357909009017560
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摘要: Methods of assessing and reporting toxic reactions induced by therapy, particularly chemotherapy, need improvements. Accurate reliable therapy-induced toxicity will be necessary for quality clinical research including drug development implementation complex multimodality treatments, currently, however, the extent vary widely. Whereas standard widely accepted criteria have been established therapeutic response, no such exist toxicity. We developed comprehensive reliably reactions. reduced degree subjectivity in assigning grades using primarily objective methods. An attempt has made to standardize "morbidity impact" each grade irrespective organ system involved.