Correlation between plasma and urinary caffeine levels in preterm infants
作者： Luigi Cattarossi , Marco Violino , Franco Macagno , Paolo LoGreco , Marilena Savoia
DOI: 10.1515/JPM.2006.067
关键词:
摘要: Background: We hypothesize that urine levels might be reliable to assess the therapeutic range of caffeine. Objectives: correlated plasma and urinary caffeine in preterm infants treated with this drug for apnea prematurity. Methods: Infants (n=56) were given a loading dose citrate (10 mg/kg, per os) 24 h later maintenance (2 os, once day). Plasma determined after (before administration dose) then weekly. Results: correlate at all examined ages: '29 weeks (r=0.92, P<0.001), 30 (r=0.97, 31 (r=0.82, 32 33 (r=0.87, 34 (r=0.81, P<0.001). Conclusion: Urinary useful means ranges.
sci-hub.se 参考文章(11)
A. Aldridge, J. V. Aranda, A. H. Neims, Caffeine metabolism in the newborn Clinical Pharmacology & Therapeutics. ,vol. 25, pp. 447- 453 ,(1979) , 10.1002/CPT1979254447
Gary Ginsberg, Dale Hattis, Abel Russ, Babasaheb Sonawane, Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: implications for assessing children's risks from environmental agents. Journal of Toxicology and Environmental Health. ,vol. 67, pp. 297- 329 ,(2004) , 10.1080/15287390490273550
Barbara Gannon, Theophylline or caffeine: which is best for apnea of prematurity? Neonatal network : NN. ,vol. 19, pp. 33- 36 ,(2000) , 10.1891/0730-0832.19.8.33
Lilia Curzi-Dascalova, Yanick Aujard, Claude Gaultier, Mandevi Rajguru, Sleep organization is unaffected by caffeine in premature infants The Journal of Pediatrics. ,vol. 140, pp. 766- 771 ,(2002) , 10.1067/MPD.2002.124383
James L. Mills, Patricia H. Shiono, Leona R. Shapiro, Patricia B. Crawford, George G. Rhoads, Early growth predicts timing of puberty in boys: results of a 14-year nutrition and growth study. The Journal of Pediatrics. ,vol. 109, pp. 543- 547 ,(1986) , 10.1016/S0022-3476(86)80141-X
N. Sekkat, A. Naik, Y.N. Kalia, P. Glikfeld, R.H. Guy, Reverse iontophoretic monitoring in premature neonates: feasibility and potential Journal of Controlled Release. ,vol. 81, pp. 83- 89 ,(2002) , 10.1016/S0168-3659(02)00046-9
C. Hoecker, M. Nelle, J. Poeschl, B. Beedgen, O. Linderkamp, Caffeine Impairs Cerebral and Intestinal Blood Flow Velocity in Preterm Infants Pediatrics. ,vol. 109, pp. 784- 787 ,(2002) , 10.1542/PEDS.109.5.784
Saleh Al-Alaiyan, Sameer Al-Rawithi, Dale Raines, Ahmed Yusuf, Erlinda Legayada, Mohamed M. Shoukri, Adnan El-Yazigi, Caffeine metabolism in premature infants. The Journal of Clinical Pharmacology. ,vol. 41, pp. 620- 627 ,(2001) , 10.1177/00912700122010500
David Millar, Barbara Schmidt, Controversies surrounding xanthine therapy. Seminars in Neonatology. ,vol. 9, pp. 239- 244 ,(2004) , 10.1016/J.SINY.2003.11.008
Saskia N de Wildt, Katja TM Kerkvliet, Muriël GA Wezenberg, Sabine Ottink, Wim CJ Hop, Arnold G Vulto, John N van den Anker, None, Use of saliva in therapeutic drug monitoring of caffeine in preterm infants. Therapeutic Drug Monitoring. ,vol. 23, pp. 250- 254 ,(2001) , 10.1097/00007691-200106000-00011