Phase I dose-escalation study of XL147, a PI3K inhibitor administered orally to patients with solid tumors

作者: G. Shapiro , E. Kwak , J. Baselga , J. Rodon , C. Scheffold

DOI: 10.1200/JCO.2009.27.15_SUPPL.3500

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摘要: 3500 Background: XL147 is a selective inhibitor of Class I PI3K isoforms. In preclinical cancer models cytostatic or cytoreductive as monotherapy and enhances the efficacy targeted agen...

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