Salts and solid forms of isoquinolinones and composition comprising and methods of using the same

作者: Andrew B. Hague , Alexander Redvers Eberlin , Ludovic Sylvain Marc Renou , Daniel G. Genov , Louis Grenier

DOI:

关键词: Organic chemistryChemistryComposition (visual arts)Kinase activityStereochemistry

摘要: Solid forms of chemical compounds that modulate kinase activity, including PI3 and compounds, pharmaceutical compositions, methods treatment diseases conditions associated with are described herein. Also provided herein processes for preparing solid thereof, compositions thereof.

参考文章(708)
Peter K. Vogt, Jonathan R. Hart, Marco Gymnopoulos, Hao Jiang, Sohye Kang, Andreas G. Bader, Li Zhao, Adam Denley, Phosphatidylinositol 3-Kinase: The Oncoprotein Current Topics in Microbiology and Immunology. ,vol. 347, pp. 79- 104 ,(2010) , 10.1007/82_2010_80
Otto-Henning Wilhelms, Androniki Roesch, Wolfgang Schaumann, Wolfgang Kampe, Use of adenosine derivatives as anti-allergic compounds and pharmaceutical compositions containing them ,(1985)
C. Vitali, M. Sciuto. S. Bombardieri, Immunotherapy in Rheumatoid Arthritis: A Review The International Journal of Artificial Organs. ,vol. 16, pp. 196- 200 ,(1993) , 10.1177/039139889301605S44
Ashley Haase, Michel Brahic, Linda Stowring, Hubert Blum, Detection of Viral Nucleic Acids by in Situ Hybridization Methods in Virology. ,vol. 7, pp. 189- 226 ,(1984) , 10.1016/B978-0-12-470207-3.50013-9
G. Shapiro, E. Kwak, J. Baselga, J. Rodon, C. Scheffold, A. D. Laird, C. Bedell, G. Edelman, Phase I dose-escalation study of XL147, a PI3K inhibitor administered orally to patients with solid tumors Journal of Clinical Oncology. ,vol. 27, pp. 3500- 3500 ,(2009) , 10.1200/JCO.2009.27.15_SUPPL.3500
Michael Soth, Nidhi Arora, David Goldstein, Counde O'Yang, Nolan Dewdney, Tobias Gabriel, Roland Billedeau, Fused-pyrazolo pyrimidine and pyrazolo pyrimidinone derivatives and methods for using the same ,(2005)
Jennifer A. Woyach, John C. Byrd, Amy J. Johnson, Translating PI3K-Delta Inhibitors to the Clinic in Chronic Lymphocytic Leukemia: The Story of CAL-101 (GS1101). American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. pp. 691- 694 ,(2012) , 10.14694/EDBOOK_AM.2012.32.691