Metabolic Control Improves Long-Term Renal Allograft and Patient Survival in Type 1 Diabetes
作者： Christian Morath , Martin Zeier , Bernd Döhler , Jan Schmidt , Peter P. Nawroth
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摘要: It is a matter of debate whether pancreas allografts independently contribute to renal allograft and patient survival in individuals who have type 1 diabetes receive simultaneous kidney transplant (SPK). Using data from the Collaborative Transplant Study, we studied patients had were recipients deceased-donor kidneys (DDK), living-donor (LDK), or SPK. We analyzed graft rates with maximum 18 yr follow-up. DDK inferior compared LDK SPK recipients. superior initially, but demonstrated equal toward end Multivariate analysis, adjusting for pretransplantation cardiovascular risk, showed that was beyond 10th year after transplantation (hazard ratio 0.55; P = 0.005). In summary, early advantage over lost during long-term follow-up, probably as result improved glycemic control
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