作者: Tamaki Yano , Shoichiro Kurata
DOI: 10.1016/B978-0-12-405529-2.00014-7
关键词:
摘要: Autophagy functions to eliminate several types of intracellular bacteria. acts as the front line innate immunity due its rapid response infection, but mechanism induction is complicated. Upon infection host cells by bacteria, autophagosomes form targeting and recruiting factors required surround Several pathways have been identified, including ubiquitin-dependent pathway, bacterial sensor-dependent damaged vacuole- dependent each which through adapter proteins for autophagosome recruitment. Here we describe these discuss their role in elimination invasive