Sulfur mediated allylic C-H alkylation of tri- and disubstituted olefins.
作者： Gang Hu , Jiaxi Xu , Pingfan Li
DOI: 10.1021/OL5031348
关键词:
摘要: A novel transition-metal-free, sulfur mediated allylic C–H alkylation reaction through a one-pot procedure involving an ene-like step between simple olefins and activated sulfoxides to generate sulfonium intermediates, subsequent [2,3]-sigmatropic rearrangement under basic conditions give products, has been developed. This method is applicable tri- disubstituted olefin substrates in both inter- intramolecular fashions.
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