RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 6: Post-cardiac arrest care.

摘要: Objective To systematically examine the evidence for interventions after return of spontaneous circulation (ROSC) on outcomes from veterinary cardiopulmonary resuscitation and to determine important knowledge gaps. Design Standardized, systematic evaluation literature, categorization relevant articles according level quality, development consensus conclusions application concepts clinical post-cardiac arrest care. Setting Academia, referral practice, general practice. Results Fifteen standardized questions care were asked research answering these identified through structured, explicit literature database searches. The majority report in species other than dogs or cats consisted experimental work canine cardiac models. Outcome metrics reported studies widely varied ranged quantification mechanistic endpoints, such as elaboration reactive oxygen species, survival, functional neurologic outcome. Conclusions Despite near complete absence studies, process allowed formulation statements several postcardiac treatments that either supportive, mild therapeutic hypothermia controlled reoxygenation, neutral, mannitol administration seizure prophylaxis. Evidence grading transparency regards strength recommendations. Moreover, numerous gaps emerged will allow generation a road map progress care.