Pigment gallstones form as a composite of bacterial microcolonies and pigment solids.

摘要: Although previous studies have suggested that bacteria may contribute to pigment gallstone formation, the current experiments provide evidence a central role in this process. The included scanning electron microscopy (SEM) of gallstones, measurements bacterial adherence gallstones vitro, and determination glycocalyx elaboration by biliary bacteria. Gallstones from 85 patients were studied under SEM. Twenty-five (78%) 32 stones had microcolonies throughout interior stones. Bacteria absent all 35 cholesterol studied. Composite (stones with separate portions) showed within portions 14 18 cases. Biliary adhered surface vitro (90%) 39 cases, compared three (8%) Glycocalyx was elaborated isolated nine (82%) 11 either or composite gallstones. One (33%) species disease produced glycocalyx. These indicate most obtained Western cultures form as bacteria, glycocalyx, solids. found majority black well brown findings serve basis new theory stone formation which are postulated be responsible for precipitation subsequent agglomeration bilirubin pigment. results also suggest sepsis is more common because can sanctuary