Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination.

作者: D. C. Scherer , J. A. Brockman , Z. Chen , T. Maniatis , D. W. Ballard

DOI: 10.1073/PNAS.92.24.11259

关键词:

摘要: … degradation of IKBa in vivo and ubiquitin conjugation in vitro. We conclude that site-specific ubiquitination of phosphorylated I#… is phosphorylated at Ser-32 and Ser-36 and then rapidly …

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