Influence of Aspirin and Dipyridamole on Patency of Coronary Artery Bypass Grafts
作者： J.E. Mayer , W.G. Lindsay , W. Castaneda , D.M. Nicoloff
DOI: 10.1016/S0003-4975(10)60927-7
关键词:
摘要: Abstract A prospective randomized trial was performed to determine if the administration of inhibitors platelet function would improve patency coronary artery bypass grafts. Patients were operated on for intractable angina with angiographically demonstrable lesions. The left internal mammary (IMA) used lesions anterior descending (LAD). Saphenous vein grafts LAD IMA inadequate and all other vessels. Treated patients received 1,300 mg aspirin 100 dipyridamole (Persantine) orally each day. Control neither drug. returned 3 6 months after operation repeat angiography. Results analyzed by chi-square. One hundred seventy-four entered study from June, 1973, through December, 1975, 113 analyzed. In control group, 66 had 27 IMA-LAD 93 saphenous treatment 47 underwent 18 75 Ninety-eight 120 (82%) patent in 87 (94%) group (x 2 = 6.34, p 6.54,
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