Proposed revised electrophysiological criteria for chronic inflammatory demyelinating polyradiculoneuropathy.

摘要: Electrophysiological criteria for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) were proposed by an Ad Hoc Subcommittee of the American Academy Neurology (AAN) in 1991. Only 60% CIDP patients fulfilled these criteria, which therefore appear poorly sensitive. We sought to revise electrophysiological criteria. selected 40 and compared them with 35 axonal polyneuropathy, 116 Charcot-Marie-Tooth type 1A (CMT1A) disease, 66 immunoglobulin M (IgM) monoclonal gammopathy. The identified 90% patients, although 3% polyneuropathy falsely identified. For sensitivity specificity 97%, respectively. Of IgM gammaglobulin undetermined significance (MGUS) CMT1A, 100% new whereas respectively, AAN These results suggest that are more appropriate MGUS CMT1A than patients. propose have better sensitivity.