Cortisol secretion in relation to body fat distribution in obese premenopausal women.
作者： Per Mårin , Niklas Darin , Teiko Amemiya , Björn Andersson , Sverker Jern
DOI: 10.1016/0026-0495(92)90171-6
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摘要: Abstract Urinary cortisol output and serum concentrations were measured in the steady state, under “field” conditions, during standardized inhibitory stimulatory tests premenopausal, obese women, analyzed relation to adipose tissue distribution. was increased field conditions women with an elevated waist hip circumference ratio (WHR) and, particular, a large abdominal sagittal diameter, indicating visceral fat accumulation. However, dexamethasone inhibition of secretion normal. Stimulation corticotropin analogue physical (cold-pressor test) or mental (color-word mathematic) stress also showed responses cortisol, but not prolactin growth hormone concentrations. It is suggested that accumulation have due sensitivity along hypothalamic-pituitary-adrenal axis, this may be causing their abnormal depot
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