β-lipotropin in brain: Localization in hypothalamic neurons by immunoperoxidase technique
作者： E.A. Zimmerman , A. Liotta , D.T. Krieger
DOI: 10.1007/BF00224929
关键词:
摘要: β-Lipotropin (β-LPH) has been localized in hypothalamus and pituitary of sheep ox by the immunoperoxidase technique. In both species β-LPH was found perikarya arcuate neurons as well cells anterior intermediate lobes pituitary. A large number immunoreactive axons were region; some appeared to innervate other others projected portal capillaries. Stained fiber segments also scattered throughout hypothalamus. The presence hypothalamic supports possibility that brain may be a precursor for opiate-like or peptides which involved neuromodulation neurohormonal activities.
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sci-hub.se 参考文章(20)
Dorothy T. Krieger, Anthony Liotta, Toshihiro Suda, Miklos Palkovits, Michael J. Brownstein, Presence of immunoassayable β-lipotropin in bovine brain and spinal cord: Lack of concordance with ACTH concentrations Biochemical and Biophysical Research Communications. ,vol. 76, pp. 930- 936 ,(1977) , 10.1016/0006-291X(77)91591-1
L. P. RENAUD, J. B. MARTIN, P. BRAZEAU, Depressant action of TRH, LH-RH and somatostatin on activity of central neurones. Nature. ,vol. 255, pp. 233- 235 ,(1975) , 10.1038/255233A0
K Fuxe, T Hokfelt, P Eneroth, J. Gustafsson, P Skett, Prolactin-like immunoreactivity: localization in nerve terminals of rat hypothalamus. Science. ,vol. 196, pp. 899- 900 ,(1977) , 10.1126/SCIENCE.323973
G. PELLETIER, R. LECLERC, F. LABRIE, J. COTE, M CHRETIEN, M. LIS, Immunohistochemical Localization of β-Lipotropic Hormone in the Pituitary Gland Endocrinology. ,vol. 100, pp. 770- 776 ,(1977) , 10.1210/ENDO-100-3-770
Virginia M. Pickel, Donald J. Reis, Susan E. Leeman, Ultrastructural localization of substance P in neurons of spinal cord Brain Research. ,vol. 122, pp. 534- 540 ,(1977) , 10.1016/0006-8993(77)90463-2
Roger Guillemin, Endorphins, Brain Peptides That Act like Opiates New England Journal of Medicine. ,vol. 296, pp. 226- 228 ,(1977) , 10.1056/NEJM197701272960414
L. H. Lazarus, N. Ling, R. Guillemin, beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 73, pp. 2156- 2159 ,(1976) , 10.1073/PNAS.73.6.2156
J. Hughes, T. W. Smith, H. W. Kosterlitz, Linda A. Fothergill, B. A. Morgan, H. R. Morris, Identification of two related pentapeptides from the brain with potent opiate agonist activity Nature. ,vol. 258, pp. 577- 579 ,(1975) , 10.1038/258577A0
Tomas Hökfelt, Suad Efendić, Claes Hellerström, Olle Johansson, Rolf Luft, Akira Arimura, CELLULAR LOCALIZATION OF SOMATOSTATIN IN ENDOCRINE-LIKE CELLS AND NEURONS OF THE RAT WITH SPECIAL REFERENCES TO THE A1-CELLS OF THE PANCREATIC ISLETS AND TO THE HYPOTHALAMUS European Journal of Endocrinology. ,vol. 80, pp. 5- 41 ,(1975) , 10.1530/ACTA.0.080S005
R. Guillemin, N. Ling, R. Burgus, Isolation, primary structure, and synthesis of α-endorphin and γ-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity Proceedings of the National Academy of Sciences of the United States of America. ,vol. 73, pp. 3942- 3946 ,(1976) , 10.1073/PNAS.73.11.3942