Digitonin Effects on Photoreceptor Adenylate Cyclase
作者： M. W. Bitensky , R. E. Gorman , W. H. Miller
DOI: 10.1126/SCIENCE.175.4028.1363
关键词:
摘要: Adenylate cyclase is described in a number of photoreceptor membranes. Vertebrate rod outer segments contain light-regulated cyclase, and light regulation abolished by digitonin. Disruption microvilli cone rhabdomphotoreceptors also associated with loss retention full enzymic activity. The data suggest that inhibitory constraint provides systems disruption membrane structure uncouples catalytic regulatory elements.
harvard.edu
sciencemag.org参考文章(25)
Martin A. Rizack, ACTIVATION OF AN EPINEPHRINE-SENSITIVE LIPOLYTIC ACTIVITY FROM ADIPOSE TISSUE BY ADENOSINE 3',5'-PHOSPHATE. Journal of Biological Chemistry. ,vol. 239, pp. 392- 395 ,(1964) , 10.1016/S0021-9258(18)51690-2
Robert C. Haynes, The Activation of Adrenal Phosphorylase by the Adrenocorticotropic Hormone Journal of Biological Chemistry. ,vol. 233, pp. 1220- 1222 ,(1958) , 10.1016/S0021-9258(19)77372-4
L.M. Klainer, Y.-M. Chi, S.L. Freidberg, T.W. Rall, Earl W. Sutherland, Adenyl cyclase. IV. The effects of neurohormones on the formation of adenosine 3',5'-phosphate by preparations from brain and other tissues. Journal of Biological Chemistry. ,vol. 237, pp. 1239- 1243 ,(1962) , 10.1016/S0021-9258(18)60315-1
M. W. BITENSKY, V. RUSSELL, M. BLANCO, Independent variation of glucagon and epinephrine responsive components of hepatic adenyl cyclase as a function of age, sex and steroid hormones. Endocrinology. ,vol. 86, pp. 154- 159 ,(1970) , 10.1210/ENDO-86-1-154
JOHN R. TURTLE, GEORGE K. LITTLETON, DAVID M. KIPNIS, Stimulation of Insulin Secretion by Theophylline Nature. ,vol. 213, pp. 727- 728 ,(1967) , 10.1038/213727A0
Herbert J. A. Dartnall, The Visual Pigments ,(2015)
A. L. Goldberg, J. J. Singer, Evidence for a role of cyclic AMP in neuromuscular transmission. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 64, pp. 134- 141 ,(1969) , 10.1073/PNAS.64.1.134
Ira Pastan, The effect of dibutyryl cyclic 3',5'-AMP on the thyroid. Biochemical and Biophysical Research Communications. ,vol. 25, pp. 14- 16 ,(1966) , 10.1016/0006-291X(66)90632-2
H. Shimizu, J. W. Daly, C. R. Creveling, A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN Journal of Neurochemistry. ,vol. 16, pp. 1609- 1619 ,(1969) , 10.1111/J.1471-4159.1969.TB10360.X
D. A. APPLEGARTH, G. BOZOIAN, Artefact of hydrolysis of glucosamine derivatives. Nature. ,vol. 215, pp. 1382- 1382 ,(1967) , 10.1038/2151382A0