摘要: As assisted reproductive technology (ART) methods become the mainstream of infertility treatment, it has even more critical to reassess its safety. Following results a study published by Robinson Institute in New England Journal Medicine, risk ART, especially intracytoplasmic sperm injection (ICSI), never been so closely scrutinized. This paper traces origins and development ICSI, assesses risks documented literature, finally interprets implications for couples contemplating therapy. We support need continued vigilance towards ICSI importance investigating male-factor as prequel use.
hindawi.com参考文章(58)
De Iuliis Gn, Aitken Rj, Value of DNA integrity assays for fertility evaluation. Society of Reproduction and Fertility supplement. ,vol. 65, pp. 81- 92 ,(2007)
Claude Gagnon, The male gamete : from basic science to clinical applications Cache River Press. ,(1999)
Donald P. Evenson, Lorna K. Jost, Brian L. Sailer, Mammalian Sperm DNA Susceptibility to In Situ Denaturation Associated with the Presence of DNA Strand Breaks as Measured by the Terminal Deoxynucleotidyl Transferase Assay Journal of Andrology. ,vol. 16, pp. 80- 87 ,(1995) , 10.1002/J.1939-4640.1995.TB01735.X
Aleksander Giwercman, Lars Lindstedt, Mattias Larsson, Mona Bungum, Marcello Spano, Richard J. Levine, Lars Rylander, Sperm chromatin structure assay as an independent predictor of fertility in vivo: a case-control study. International Journal of Andrology. ,vol. 33, pp. 221- 227 ,(2010) , 10.1111/J.1365-2605.2009.00995.X
Marcello Spanò, Jens P Bonde, Henrik I Hjøllund, Henrik A Kolstad, Eugenia Cordelli, Giorgio Leter, Sperm chromatin damage impairs human fertility‡‡The Danish First Pregnancy Planner Study is a collaborative follow-up study on environmental and biological determinants of fertility. The project is coordinated by the Steno Institute of Public Health, Aarhus University and is undertaken in collaboration with the Department of Growth and Reproduction, National University Hospital, Copenhagen. The team includes Jens Peter E. Bonde, Niels Henrik I. Hjøllund, Tina Kold Jensen, Tine Brink Henriksen, Henrik A. Kolstad, Erik Ernst, Aleksander Giwercman, Niels Erik Skakkebæk, and Jørn Olsen. Fertility and Sterility. ,vol. 73, pp. 43- 50 ,(2000) , 10.1016/S0015-0282(99)00462-8
J. J Kurinczuk, C. Bower, Birth defects in infants conceived by intracytoplasmic sperm injection: an alternative interpretation BMJ. ,vol. 315, pp. 1260- 1266 ,(1997) , 10.1136/BMJ.315.7118.1260
K. Aittomaki, Safety issues in assisted reproduction technology Should ICSI patients have genetic testing before treatment? A practical proposition to help patient information Human Reproduction. ,vol. 19, pp. 472- 476 ,(2004) , 10.1093/HUMREP/DEH100
Emre Basatemur, Mark Shevlin, Alastair Sutcliffe, Growth of children conceived by IVF and ICSI up to 12 years of age Reproductive Biomedicine Online. ,vol. 20, pp. 144- 149 ,(2010) , 10.1016/J.RBMO.2009.10.006
Cathérine Dupont, D. Armant, Carol Brenner, Epigenetics: definition, mechanisms and clinical perspective. Seminars in Reproductive Medicine. ,vol. 27, pp. 351- 357 ,(2009) , 10.1055/S-0029-1237423
Queenie V. Neri, Takumi Takeuchi, Gianpiero D. Palermo, An Update of Assisted Reproductive Technologies Results in the United States Annals of the New York Academy of Sciences. ,vol. 1127, pp. 41- 48 ,(2008) , 10.1196/ANNALS.1434.017