Carbon-13 nuclear magnetic resonance studies of coumarin and related compounds

作者: Kenneth K. Chan , Donald D. Giannini , Anne H. Cain , John D. Roberts , William Porter

DOI: 10.1016/0040-4020(77)80043-4

关键词:

摘要: Fourier-transform ^(13)C NMR spectra of nine coumarinoid compounds medicinal interest are reported. All the carbon resonances assigned with aid various spectral techniques and stable isotopic labeling. The substituent effects on chemical shifts in several systems also discussed.

参考文章(18)
Maxwell. Bullpitt, William. Kitching, David. Doddrell, William. Adcock, Substituent effect of the bromomethyl group. Carbon-13 magnetic resonance study Journal of Organic Chemistry. ,vol. 41, pp. 760- 766 ,(1976) , 10.1021/JO00867A003
Nancy K Wilson, J.B Stothers, 13C and 1H spectra of some methylnaphthalenes Journal of Magnetic Resonance. ,vol. 15, pp. 31- 39 ,(1974) , 10.1016/0022-2364(74)90171-1
Otto A. Gansow, Werner Schittenheim, Alternately pulsed carbon-13 and proton magnetic resonance, an alternative to nuclear off-resonance decoupling Journal of the American Chemical Society. ,vol. 93, pp. 4294- 4295 ,(1971) , 10.1021/JA00746A036
Kenneth K. Chan, Richard J. Lewis, William F. Trager, Absolute configurations of the four warfarin alcohols Journal of Medicinal Chemistry. ,vol. 15, pp. 1265- 1270 ,(1972) , 10.1021/JM00282A016
Lance R. Pohl, Rodney Haddock, William A. Garland, William F. Trager, Synthesis and thin-layer chromatographic ultraviolet, and mass spectral properties of the anticoagulant phenprocoumon and its monohydroxylated derivatives. Journal of Medicinal Chemistry. ,vol. 18, pp. 513- 519 ,(1975) , 10.1021/JM00239A016
Paul C. Lauterbur, C13 Nuclear Magnetic Resonance Spectroscopy. II. Phenols, Anisole and Dimethoxybenzenes Journal of the American Chemical Society. ,vol. 83, pp. 1846- 1852 ,(1961) , 10.1021/JA01469A018
Dieter Lauer, Edwin L. Motell, Daniel D. Traficante, Gary E. Maciel, Carbon-13 chemical shifts in monoalkyl benzenes and some deuterio analogs Journal of the American Chemical Society. ,vol. 94, pp. 5335- 5338 ,(1972) , 10.1021/JA00770A032
Donald. Valentine, K. K. Chan, C. G. Scott, K. K. Johnson, K. Toth, G. Saucy, Direct determinations of R/S enantiomer ratios of citronellic acid and related substances by nuclear magnetic resonance spectroscopy and high pressure liquid chromatography Journal of Organic Chemistry. ,vol. 41, pp. 62- 65 ,(1976) , 10.1021/JO00863A014
Miyoshi Ikawa, Mark Arnold Stahmann, Karl Paul Link, Studies on 4-Hydroxycoumarins. V. The Condensation of α,β-Unsaturated Ketones with 4-Hydroxycoumarin1 Journal of the American Chemical Society. ,vol. 66, pp. 902- 906 ,(1944) , 10.1021/JA01234A019