DNA repair and cancer : from bench to clinic

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DOI: 10.1201/B14587

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摘要: Overview of DNA Repair Pathways Longevity Assurance by Genome Maintenance Instability Cancer: Biological Predictions and Clinical Implications Radiation Induced Damage, Therapeutics Chemotherapeutic Alkylating Agents in Cancer Treatment O6-Methylguanine-DNA Methyltransferase (MGMT) Protection Therapy Mismatch Repair: It's Role Human Carcinogenesis as a Predictive and/or Prognostic Biomarker for Base Excision Therapeutics: Summary Targets with Focus on APE1 Nucleotide Capacity Variability Susceptibility Fanconi Anemia, Interstrand Cross-link Functions Translesion Polymerases: Risk Opportunities Therapeutic p53 ATM/ATR Cell Cycle Checkpoints: Mechanisms Manipulation The BRCA1-BRCA2 Pathway Homologous Recombination the Opportunity Synthetic Lethal Approaches to PARP Inhibitor Tumor Genetics Personalized Medicine Microenvironment Progression Early Phase Trials using Inhibitors: Lessons Learnt

参考文章(9)
Neidhard Paweletz, Walther Flemming: pioneer of mitosis research Nature Reviews Molecular Cell Biology. ,vol. 2, pp. 72- 75 ,(2001) , 10.1038/35048077
A. D. Hershey, Martha Chase, Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage. The Journal of General Physiology. ,vol. 36, pp. 39- 56 ,(1952) , 10.1085/JGP.36.1.39
J. E. CLEAVER, Defective repair replication of DNA in xeroderma pigmentosum. Nature. ,vol. 218, pp. 652- 656 ,(1968) , 10.1038/218652A0
A. Kelner, Effect of Visible Light on the Recovery of Streptomyces Griseus Conidia from Ultra-violet Irradiation Injury Proceedings of the National Academy of Sciences. ,vol. 35, pp. 73- 79 ,(1949) , 10.1073/PNAS.35.2.73
J. E. Cleaver, XERODERMA PIGMENTOSUM: A HUMAN DISEASE IN WHICH AN INITIAL STAGE OF DNA REPAIR IS DEFECTIVE Proceedings of the National Academy of Sciences of the United States of America. ,vol. 63, pp. 428- 435 ,(1969) , 10.1073/PNAS.63.2.428
J. D. WATSON, F. H. C. CRICK, Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid Nature. ,vol. 171, pp. 737- 738 ,(1953) , 10.1038/171737A0
Johana Vázquez-Matías, Irene M Jones, Tong Xi, Harvey W Mohrenweiser, Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans. Cancer Epidemiology, Biomarkers & Prevention. ,vol. 11, pp. 1054- 1064 ,(2002)