Keratin 16 regulates innate immunity in response to epidermal barrier breach

作者: J. C. Lessard , S. Pina-Paz , J. D. Rotty , R. P. Hickerson , R. L. Kaspar

DOI: 10.1073/PNAS.1309576110

关键词:

摘要: Mutations in the type I keratin 16 (Krt16) and its partner type II keratin 6 (Krt6a, Krt6b) cause pachyonychia congenita (PC), a disorder typified by dystrophic nails, painful hyperkeratotic …

参考文章(67)
Kavita Deonarine, Monica C Panelli, Mitchell E Stashower, Ping Jin, Kina Smith, Herbert B Slade, Christopher Norwood, Ena Wang, Francesco M Marincola, David F Stroncek, Gene expression profiling of cutaneous wound healing. Journal of Translational Medicine. ,vol. 5, pp. 11- 11 ,(2007) , 10.1186/1479-5876-5-11
John B. Mee, Claire M. Johnson, Nilesh Morar, Frank Burslem, Richard W. Groves, The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: dominance of innate immune responses in psoriasis. American Journal of Pathology. ,vol. 171, pp. 32- 42 ,(2007) , 10.2353/AJPATH.2007.061067
Kristin Seltmann, Wera Roth, Cornelia Kröger, Fanny Loschke, Marcell Lederer, Stefan Hüttelmaier, Thomas M. Magin, Keratins Mediate Localization of Hemidesmosomes and Repress Cell Motility Journal of Investigative Dermatology. ,vol. 133, pp. 181- 190 ,(2013) , 10.1038/JID.2012.256
Victor W. Wong, Satoshi Akaishi, Michael T. Longaker, Geoffrey C. Gurtner, Pushing Back: Wound Mechanotransduction in Repair and Regeneration Journal of Investigative Dermatology. ,vol. 131, pp. 2186- 2196 ,(2011) , 10.1038/JID.2011.212
Richard L. Eckert, Ann-Marie Broome, Monica Ruse, Nancy Robinson, David Ryan, Kathleen Lee, S100 Proteins in the Epidermis Journal of Investigative Dermatology. ,vol. 123, pp. 23- 33 ,(2004) , 10.1111/J.0022-202X.2004.22719.X
Joost J Oppenheim, De Yang, Alarmins: chemotactic activators of immune responses. Current Opinion in Immunology. ,vol. 17, pp. 359- 365 ,(2005) , 10.1016/J.COI.2005.06.002
Sancy A. Leachman, Roger L. Kaspar, Philip Fleckman, Scott R. Florell, Frances J.D. Smith, W.H. Irwin McLean, Declan P. Lunny, Leonard M. Milstone, Maurice A.M. van Steensel, Colin S. Munro, Edel A. O'Toole, Julide T. Celebi, Aleksej Kansky, EBirgitte Lane, Clinical and Pathological Features of Pachyonychia Congenita Journal of Investigative Dermatology Symposium Proceedings. ,vol. 10, pp. 3- 17 ,(2005) , 10.1111/J.1087-0024.2005.10202.X
Leonard M. Milstone, Philip Fleckman, Sancy A. Leachman, Irene M. Leigh, Amy S. Paller, Maurice A.M. van Steensel, Carl Swartling, Treatment of Pachyonychia Congenita Journal of Investigative Dermatology Symposium Proceedings. ,vol. 10, pp. 18- 20 ,(2005) , 10.1111/J.1087-0024.2005.10203.X
Kenzo Takahashi, Bing Yan, Kiyofumi Yamanishi, Sadao Imamura, Pierre A. Coulombe, The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs. Genomics. ,vol. 53, pp. 170- 183 ,(1998) , 10.1006/GENO.1998.5476