Epidemiology of herpes simplex virus type 1 and 2 in Italy: a seroprevalence study from 2000 to 2014.

摘要: Herpes simplex viruses (HSV) are among the most widespread causative agents of human viral infections. HSV-2 is one commonest causes genital disease, while HSV-1 associated primarily with orolabial ulceration; however, recent changes in HSV epidemiology showed an increase and neonatal herpes particularly caused by HSV-1. The main purpose this study was to assess seroprevalence a random population Siena (central Italy) 2000, 2005 2013-2014 Bari (southern 2005. Moreover, preliminary conducted investigate spread infection pregnant women infants 2003, 2004 Human serum samples were tested for presence specific anti-HSV-1 anti-HSV-2 IgG antibodies using commercially available ELISA test. For primary purpose, rates observed compared over years sampled rate found Bari. Results show decreased trend both viruses, especially adolescents young adults; moreover, two cities suggest geographical differences. secondary prevalence general population. No significant difference women, results indicate source infants.