Peaaju difuussete astrotsütaarsete glioomide loomupärane invasiivsus

作者: Tambet Teesalu , Andres Kulla , Toomas Asser

DOI: 10.15157/EA.V0I0.9473

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摘要: Inimese astrotsutaarsetele glioomidele iseomane invasiivne kaitumine on uheks peamiseks probleemiks neuroonkoloogias. Astrotsutoomirakkude migratsioon aluseks nende kasvajate ulatuslikule levikule narvisusteemis, mis raskendab oluliselt kasvaja piiride kindlaksmaaramist diagnostikas ning viib sageli kirurgilisele ja adjuvantravile vaatamata kasvajahaiguse retsidiveerumisele. Invasioonimehhanismide moistmine oluliseks ehk ka eelduseks leidmaks potentsiaalseid ravistrateegilisi rundepunkte astrotsutaarse rea efektiivseks kasitlemiseks lahitulevikus. Eesti Arst 2003; 82 (10): 699–706

参考文章(23)
S. Yamamoto, Y. Ushio, J.-I. Kuratsu, Y. Saitoh, H. Takeshima, Expression of osteopontin in human glioma. Its correlation with the malignancy. Laboratory Investigation. ,vol. 72, pp. 55- 63 ,(1995)
Joseph M. Piepmeier, Gail M. Kelly, Susan Hockfield, Diane M. Jaworski, BEHAB (Brain Enriched Hyaluronan Binding) Is Expressed in Surgical Samples of Glioma and in Intracranial Grafts of Invasive Glioma Cell Lines Cancer Research. ,vol. 56, pp. 2293- 2298 ,(1996)
Alf Giese, Michael E. Berens, Melinda A. Loo, Monique D. Rief, Determinants of Human Astrocytoma Migration Cancer Research. ,vol. 54, pp. 3897- 3904 ,(1994)
Berit B. Tysnes, Lone F. Larsen, Gro O. Ness, Rupavathana Mahesparan, Klaus Edvardsen, Inmaculada Garcia-Cabrera, Rolf Bjerkvig, Stimulation of glioma‐cell migration by laminin and inhibition by anti‐α3 and anti‐β1 integrin antibodies International Journal of Cancer. ,vol. 67, pp. 777- 784 ,(1996) , 10.1002/(SICI)1097-0215(19960917)67:6<777::AID-IJC5>3.0.CO;2-O
H Birkedal-Hansen, Proteolytic remodeling of extracellular matrix Current Opinion in Cell Biology. ,vol. 7, pp. 728- 735 ,(1995) , 10.1016/0955-0674(95)80116-2
Karl H. Plate, Werner Risau, Angiogenesis in malignant gliomas Glia. ,vol. 15, pp. 339- 347 ,(1995) , 10.1002/GLIA.440150313
Shahriar Koochekpour, Geoffrey J. Pilkington, Abderrahim Merzak, Hyaluronic acid/CD44H interaction induces cell detachment and stimulates migration and invasion of human glioma cells in vitro International Journal of Cancer. ,vol. 63, pp. 450- 454 ,(1995) , 10.1002/IJC.2910630325
Rolf Bjerkvig, Morten Lund-Johansen, Klaus Edvardsen, Tumor cell invasion and angiogenesis in the central nervous system. Current Opinion in Oncology. ,vol. 9, pp. 223- 229 ,(1997) , 10.1097/00001622-199709030-00002
Paul Kleihues, Leslie H Sobin, None, World Health Organization classification of tumors. Cancer. ,vol. 88, pp. 2887- 2887 ,(2000) , 10.1002/1097-0142(20000615)88:12<2887::AID-CNCR32>3.0.CO;2-F