A structural model used to evaluate the changing microstructure of maturing rat skin
作者： S.M. Belkoff , R.C. Haut
DOI: 10.1016/0021-9290(91)90335-K
关键词:
摘要: A microstructurally based model for soft biological tissues was adapted to the non-linear response of collagenous network in skin. Quasi-static uniaxial tensile tests were conducted on dorsal skin rats aged 1–4 months. Specimens taken longitudinally and transversely (laterally) spine tested at 1.5% s−1. The showed fiber stiffness increase laterally during maturation be greater than longitudinally. It also indicated migration ‘heel’ portion curve toward origin due less crimping fibers. These results qualitatively supported by microscopical observations. found well suited fit curves exhibiting a well-defined region. For more flat, featureless region (typical 1 month longitudinal specimens) not suited. this study indicate that simple three-parameter might useful tool future studies analyze pathological changes microstructure.
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sci-hub.se 参考文章(32)
H. G. Vogel, D. Kobelt, G. W. Korting, W. Holzmann, Pr�fung der Festigkeitseigenschaften von Rattenhaut in Abh�ngigkeit von Lebensalter und Geschlecht Archiv f�r Klinische und Experimentelle Dermatologie. ,vol. 239, pp. 296- 306 ,(1970) , 10.1007/BF00520344
J.E. CRAIK, I.R.R. MCNEIL, HISTOLOGICAL STUDIES OF STRESSED SKIN Biomechanics and Related Bio-Engineering Topics#R##N#Proceedings of a Symposium Held in Glasgow, September 1964. pp. 159- 164 ,(1965) , 10.1016/B978-1-4831-6701-5.50023-1
M.D. Ridge, V. Wright, The Directional Effects of Skin Journal of Investigative Dermatology. ,vol. 46, pp. 341- 346 ,(1966) , 10.1038/JID.1966.54
Anne-Marie Hult, Robert W. Goltz, The Measurement of Elastin in Human Skin and its Quantity in Relation to Age* Journal of Investigative Dermatology. ,vol. 44, pp. 408- 412 ,(1965) , 10.1038/JID.1965.74
Maria Comninou, I.V. Yannas, Dependence of stress-strain nonlinearity of connective tissues on the geometry of collagen fibres Journal of Biomechanics. ,vol. 9, pp. 427- 433 ,(1976) , 10.1016/0021-9290(76)90084-1
H. Alexander, T.H. Cook, ACCOUNTING FOR NATURAL TENSION IN THE MECHANICAL TESTING OF HUMAN SKIN Journal of Investigative Dermatology. ,vol. 69, pp. 310- 314 ,(1977) , 10.1111/1523-1747.EP12507731
IAN A. BROWN, A scanning electron microscope study of the effects of uniaxial tension on human skin. British Journal of Dermatology. ,vol. 89, pp. 383- 393 ,(2006) , 10.1111/J.1365-2133.1973.TB02993.X
Y. Lanir, A structural theory for the homogeneous biaxial stress-strain relationships in flat collagenous tissues Journal of Biomechanics. ,vol. 12, pp. 423- 436 ,(1979) , 10.1016/0021-9290(79)90027-7
R. C. Haut, The effects of orientation and location on the strength of dorsal rat skin in high and low speed tensile failure experiments. Journal of Biomechanical Engineering-transactions of The Asme. ,vol. 111, pp. 136- 140 ,(1989) , 10.1115/1.3168354
EVA BOTTOMS, SAM SHUSTER, EFFECT OF ULTRA-VIOLET LIGHT ON SKIN COLLAGEN. Nature. ,vol. 199, pp. 192- 193 ,(1963) , 10.1038/199192A0