Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse.
作者： Paula A. Coelho , Leah Bury , Marta N. Shahbazi , Kifayathullah Liakath-Ali , Peri H. Tate
DOI: 10.1098/RSOB.150209
关键词:
摘要: To address the long-known relationship between supernumerary centrosomes and cancer, we have generated a transgenic mouse that permits inducible expression of the master …
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