Comparative Assessment of the Accuracy of Cytological and Histologic Biopsies in the Diagnosis of Canine Bone Lesions

摘要: Background Osteosarcoma (OSA) should be differentiated from other less frequent primary bone neoplasms, metastatic disease, and tumor-like lesions, as treatment prognosis can vary accordingly. Hence, a preoperative histologic diagnosis is generally preferred. This requires collection of multiple biopsies under general anesthesia, with possible complications, including pathological fractures. Fine-needle aspiration cytology would allow an earlier significant reduction discomfort morbidity. Hypothesis/Objectives The aim this study was to compare the accuracy cytological in canine osteodestructive lesions. Animals Sixty-eight dogs lesions. Methods Retrospective study. Accuracy assessed by comparing former final on surgical or post-mortem samples or, case non-neoplastic follow-up information. Results The included 50 malignant tumors (40 OSAs, 5 chondrosarcomas, 2 fibrosarcomas, 3 poorly sarcomas), 6 carcinoma metastases, 12 lesions. 83% for (sensitivity, 83.3%; specificity, 80%) 82.1% histology 72.2%; 100%). Tumor type correctly identified cytologically histologically 55.5% cases, respectively. Conclusions Clinical Importance The similar histology, even determination tumor type. In no benign lesion diagnosed cytology. most important error prevent, includes aggressive surgery. Being reliable diagnostic method, further considered aid decisions setting