Toward a convergence of regenerative medicine, rehabilitation, and neuroprosthetics.
作者： Shyam Aravamudhan , Ravi V. Bellamkonda
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摘要: Abstract No effective therapeutic interventions exist for severe neural pathologies, despite significant advances in regenerative medicine, rehabilitation, and neuroprosthetics. Our current hypothesis is that a specific combination of tissue engineering, pharmacology, cell replacement, drug delivery, electrical stimulation, together with plasticity-promoting locomotor training (neurorehabilitation) necessary to interact synergistically order activate enable all damaged circuits. We postulate various convergent themes among the different fields. Therefore, objective this review highlight themes, which we believe have common goal restoring function after damage. The discussed include modulation inflammation secondary damage, encouraging endogenous repair/regeneration (using scaffolds, transplantation, delivery), application fields modulate healing and/or ...
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