摘要: Schilddrusenhormone haben wahrend einer Schwangerschaft profunde Auswirkungen auf die kindliche Entwicklung und mutterliche Gesundheit. Schilddrusenfehlfunktionen mussen daher rechtzeitig diagnostiziert adaquat behandelt werden. Schwangerschaftsspezifische physiologische Veranderungen fuhren unter anderem dazu, dass der Referenzbereich des thyreoideastimulierenden Hormons verandert ist trimesterspezifische Grenzwerte beachtet werden mussen. Dieser Beitrag fasst wichtigsten diagnostischen therapeutischen Aspekte vor, nach zusammen. Bezuglich Zeit vor wird Jodidsupplementation, prakonzeptionelle Untersuchung Schilddrusenstoffwechsellage Bedeutung von Schilddrusenfunktionsstorungen fur Fertilitat Erfullung Kinderwunschs eingegangen. Mit Blick Hypothyroxinamie, Hypothyreose Hyperthyreose sowie Effekte ihrer Therapie Kindes erortert. Zuletzt beschrieben, was in Stillzeit bei Postpartumthyreoiditis zu beachten ist.
springer.com
sci-hub.se 参考文章(15)
R. Vissenberg, M.M. van Dijk, E. Fliers, J.A.M. van der Post, M. van Wely, K.W.M. Bloemenkamp, A. Hoek, W.K. Kuchenbecker, H.R. Verhoeve, H.C.J. Scheepers, S. Rombout-de Weerd, C. Koks, J.J. Zwart, F. Broekmans, W. Verpoest, O.B. Christiansen, M. Post, D.N.M. Papatsonis, M.F.G. Verberg, J. Sikkema, B.W. Mol, P.H. Bisschop, M. Goddijn, Effect of levothyroxine on live birth rate in euthyroid women with recurrent miscarriage and TPO antibodies (T4-LIFE study) Contemporary Clinical Trials. ,vol. 44, pp. 134- 138 ,(2015) , 10.1016/J.CCT.2015.08.005
Susan J. Mandel, David S. Cooper, The Use of Antithyroid Drugs in Pregnancy and Lactation The Journal of Clinical Endocrinology and Metabolism. ,vol. 86, pp. 2354- 2359 ,(2001) , 10.1210/JCEM.86.6.7573
Erik K. Alexander, Elizabeth N. Pearce, Gregory A. Brent, Rosalind S. Brown, Herbert Chen, Chrysoula Dosiou, William A. Grobman, Peter Laurberg, John H. Lazarus, Susan J. Mandel, Robin P. Peeters, Scott Sullivan, GUIDELINES OF THE AMERICAN THYROID ASSOCIATION FOR THE DIAGNOSIS AND MANAGEMENT OF THYROID DISEASE DURING PREGNANCY AND POSTPARTUM Thyroid. ,vol. 21, pp. 1081- 1125 ,(2011) , 10.1089/THY.2016.0457
Stine Linding Andersen, Jørn Olsen, Chun Sen Wu, Peter Laurberg, Birth Defects After Early Pregnancy Use of Antithyroid Drugs: A Danish Nationwide Study The Journal of Clinical Endocrinology and Metabolism. ,vol. 98, pp. 4373- 4381 ,(2013) , 10.1210/JC.2013-2831
David S Cooper, Peter Laurberg, Hyperthyroidism in pregnancy The Lancet Diabetes & Endocrinology. ,vol. 1, pp. 238- 249 ,(2013) , 10.1016/S2213-8587(13)70086-X
Marco Medici, Tim I M Korevaar, W Edward Visser, Theo J Visser, Robin P Peeters, Thyroid Function in Pregnancy: What is Normal? Clinical Chemistry. ,vol. 61, pp. 704- 713 ,(2015) , 10.1373/CLINCHEM.2014.236646
Tim I M Korevaar, Ryan Muetzel, Marco Medici, Layal Chaker, Vincent W V Jaddoe, Yolanda B de Rijke, Eric A P Steegers, Theo J Visser, Tonya White, Henning Tiemeier, Robin P Peeters, Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study. The Lancet Diabetes & Endocrinology. ,vol. 4, pp. 35- 43 ,(2016) , 10.1016/S2213-8587(15)00327-7
Eleonore Fröhlich, Richard Wahl, MECHANISMS IN ENDOCRINOLOGY: Impact of isolated TSH levels in and out of normal range on different tissues. European Journal of Endocrinology. ,vol. 174, ,(2015) , 10.1530/EJE-15-0713
Spyridoula Maraka, Raphael Mwangi, Rozalina G McCoy, Xiaoxi Yao, Lindsey R Sangaralingham, Naykky M Singh Ospina, Derek T O’Keeffe, Ana E Espinosa De Ycaza, Rene Rodriguez-Gutierrez, Charles C Coddington, Marius N Stan, Juan P Brito, Victor M Montori, Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment. BMJ. ,vol. 356, pp. 58- 65 ,(2017) , 10.1136/BMJ.I6865
Brian M. Casey, Elizabeth A. Thom, Alan M. Peaceman, Michael W. Varner, Yoram Sorokin, Deborah G. Hirtz, Uma M. Reddy, Ronald J. Wapner, John M. Thorp, George Saade, Alan T.N. Tita, Dwight J. Rouse, Baha Sibai, Jay D. Iams, Brian M. Mercer, Jorge Tolosa, Steve N. Caritis, J. Peter VanDorsten, Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy The New England Journal of Medicine. ,vol. 376, pp. 815- 825 ,(2017) , 10.1056/NEJMOA1606205