A phase II trial of ixabepilone in Asian patients with advanced gastric cancer previously treated with fluoropyrimidine-based chemotherapy
作者： Yeul Hong Kim , Kei Muro , Hirofumi Yasui , Jen-Shi Chen , Min-Hee Ryu
DOI: 10.1007/S00280-012-1943-6
关键词:
摘要: Purpose The highest rates of gastric cancer occur in Eastern Asia. Fluoropyrimidine-based therapy is used initially unresectable and metastatic disease, but no single standard care exists following disease progression. Ixabepilone, an epothilone B analog, a non-taxane microtubule-stabilizing agent with clinical activity across multiple tumor types approved by the United States Food Drug Administration for treatment breast cancer.
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