Asian patients with gastric carcinoma in the United States exhibit unique clinical features and superior overall and cancer specific survival rates.

作者: Charles P. Theuer , Tom Kurosaki , Argyrios Ziogas , John Butler , Hoda Anton‐Culver

DOI: 10.1002/1097-0142(20001101)89:9<1883::AID-CNCR3>3.3.CO;2-8

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摘要: BACKGROUND. The 5-year survival rate from gastric carcinoma, stratified by stage, is markedly greater in the Far East than United States. This advantage may reflect differences diagnostic criteria, more complete staging, radical surgery, or less aggressive tumor biology. METHODS. A historic cohort of consecutive cases carcinoma reported to population-based California Cancer Registries Orange, San Diego and Imperial Counties 1984 1996 was studied. Factors associated with Asian race were profiled using logistic regression. Multivariate analyses performed a Cox proportional hazard model. RESULTS. Two thousand four hundred sixteen patients (64%) non-Latino white; 690 (18%) Latino; 94 (2.5%) black; 541 (14%) descent: Korean (22%), Vietnamese (20%), Japanese Chinese (14%), Filipino (12%). likely have localized (lymph node negative) disease (odds ratio [OR], 1.61; 95% confidence interval [CI], 1.23‐2.10), tumors gastroesophageal junction (OR, 0.22; CI, 0.15‐ 0.31,), be older 50 years 0.58; 0.43‐ 0.77). twice as whites alive at 5 (20.9% vs. 10.2%; P , 0.0001). indicated that had an increased risk dying all causes (relative [RR], 1.34; 1.16 ‐1.55; 0.01) cancer comparison (RR, 1.26; 1.07‐1.48; 0.05). CONCLUSIONS. Asians who received diagnosis States advanced non-Asians. proportion improved rates descent consistent 2000;89: 1883‐92. © 2000 American Society.

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