Systematic review reveals heterogeneity in definition of a clinically relevant difference in pain
作者： Adeline Ruyssen-Witrand , Florence Tubach , Philippe Ravaud
DOI: 10.1016/J.JCLINEPI.2010.06.008
关键词:
摘要: Abstract Objective To describe the pain decrease considered as clinically relevant when designing a trial and reporting its results. Methods A systematic review of literature in MEDLINE was conducted to select randomized controlled trials (RCTs) with primary outcome. Data extracted included definition (terms values) difference pain, type studied (acute or chronic), level application (group individual) difference, reference justifying choice value for difference. Study Design Setting Seventy-four were included, only 16 articles justified citation. The values chosen relative varied from 4 40 mm 15% 55% at group 20 50 mm individual level. In seven articles, authors confused Conclusion Our revealed great heterogeneity definition, format, what is RCTs analgesics, standardizations are advisable.
elsevier.com
sci-hub.se 参考文章(53)
Roman Jaeschke, Joel Singer, Gordon H. Guyatt, Measurement of health status: Ascertaining the minimal clinically important difference Controlled Clinical Trials. ,vol. 10, pp. 407- 415 ,(1989) , 10.1016/0197-2456(89)90005-6
Vibeke Strand, Claire Bombardier, James G. Wright, George Wells, Dorcas E. Beaton, Jeffrey N. Katz, Maarten Boers, Beverly Shea, Looking for important change/differences in studies of responsiveness. OMERACT MCID Working Group. Outcome Measures in Rheumatology. Minimal Clinically Important Difference. The Journal of Rheumatology. ,vol. 28, pp. 400- 405 ,(2001)
David T Felson, Philippe Ravaud, Florence Tubach, Claire Bombardier, George Wells, Dorcas Beaton, Maarten Boers, Desireé van der Heijde, Maxime Dougados, Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disorders. The Journal of Rheumatology. ,vol. 34, pp. 1188- 1193 ,(2007)
E. Qerama, A. Fuglsang-Frederiksen, H. Kasch, F. W. Bach, T. S. Jensen, A double-blind, controlled study of botulinum toxin A in chronic myofascial pain. Neurology. ,vol. 67, pp. 241- 245 ,(2006) , 10.1212/01.WNL.0000224731.06168.DF
Douglas G Altman, Patrick Royston, The cost of dichotomising continuous variables BMJ. ,vol. 332, pp. 1080- 1080 ,(2006) , 10.1136/BMJ.332.7549.1080
Marcos Renato Assis, Luciana Eduardo Silva, Adriana Martins Barros Alves, Ana Paula Pessanha, Valéria Valim, Daniel Feldman, Turíbio Leite de Barros Neto, Jamil Natour, A randomized controlled trial of deep water running: clinical effectiveness of aquatic exercise to treat fibromyalgia. Arthritis & Rheumatism. ,vol. 55, pp. 57- 65 ,(2006) , 10.1002/ART.21693
Brendan Carvalho, Larry Chu, Andrea Fuller, Sheila E. Cohen, Edward T. Riley, Valdecoxib for postoperative pain management after cesarean delivery: a randomized, double-blind, placebo-controlled study. Anesthesia & Analgesia. ,vol. 103, pp. 664- 670 ,(2006) , 10.1213/01.ANE.0000229702.42426.A6
Alparslan Turan, Dilek Memi??, Beyhan Karamanlio??lu, Turhan G??ler, Zafer Pamuk??u, Intravenous regional anesthesia using lidocaine and magnesium. Anesthesia & Analgesia. ,vol. 100, pp. 1189- 1192 ,(2005) , 10.1213/01.ANE.0000145062.39112.C5
Manzo Suzuki, Syuji Haraguti, Kikuzo Sugimoto, Takehiko Kikutani, Yoichi Shimada, Atsuhiro Sakamoto, Low-dose Intravenous Ketamine Potentiates Epidural Analgesia after Thoracotomy Anesthesiology. ,vol. 105, pp. 111- 119 ,(2006) , 10.1097/00000542-200607000-00020
Jason A. Abbott, Sherin K. Jarvis, Stephen D. Lyons, Angus Thomson, Thierry G. Vancaille, Botulinum toxin type A for chronic pain and pelvic floor spasm in women: a randomized controlled trial. Obstetrics & Gynecology. ,vol. 108, pp. 915- 923 ,(2006) , 10.1097/01.AOG.0000237100.29870.CC