Correlation between serum parathyroid hormone levels and coronary artery calcification in patients without renal failure.

作者: Gang-Yong Wu , Bai-Da Xu , Ting Wu , Xiao-Ying Wang , Tian-Xiao Wang

DOI: 10.3892/BR.2016.761

关键词:

摘要: The aim of the present study was to investigate correlation between serum parathyroid hormone (PTH) levels and coronary artery calcification (CAC) in patients without renal failure, as well determine independent risk factors CAC score (CACS). A total 157 who underwent computed tomography angiographic examination at 101th Hospital People's Liberation Army December 2013 February 2015 were retrospectively evaluated. PTH CACS determined using a Pearson analysis. receiver operating characteristic (ROC) curve drawn best cutoff level for prediction CAC. association analyzed by logistic regression analysis model with response variable Be binary class. results revealed that group significantly higher than those non-calcification group. positively correlated (r=0.288, P<0.001). ROC suggested ≥31.05 pg/ml cut-off point CAC, sensitivity 80.88%, specificity 60.67% an area under 0.761. After including predictive (gender, age, smoking status, diabetes, hypertension, hyperlipidemia, body mass index, glomerular filtration rate calcium, phosphorus, calcium-phosphorus product, magnesium, PTH, cholesterol, low-density lipoprotein triglyceride, high-density cholesterol C-reactive protein levels), odds ratio regarding 1.050 (95% confidence interval, 1.027-1.074; In conclusion, are failure may thus be used reliable predictor

参考文章(32)
Matthew J. Budoff, Leslee J. Shaw, Sandy T. Liu, Steven R. Weinstein, Philip H. Tseng, Ferdinand R. Flores, Tracy Q. Callister, Paolo Raggi, Daniel S. Berman, Tristen P. Mosler, Long-Term Prognosis Associated With Coronary Calcification: Observations From a Registry of 25,253 Patients Journal of the American College of Cardiology. ,vol. 49, pp. 1860- 1870 ,(2007) , 10.1016/J.JACC.2006.10.079
Machiko Oka, Takayasu Ohtake, Yasuhiro Mochida, Kunihiro Ishioka, Kyoko Maesato, Hidekazu Moriya, Sumi Hidaka, Shuzo Kobayashi, Correlation of Coronary Artery Calcification With Pre-Hemodialysis Bicarbonate Levels in Patients on Hemodialysis Therapeutic Apheresis and Dialysis. ,vol. 16, pp. 267- 271 ,(2012) , 10.1111/J.1744-9987.2011.01054.X
Elena Kamycheva, Johan Sundsfjord, Rolf Jorde, Serum parathyroid hormone levels predict coronary heart disease: the Tromsø Study European Journal of Preventive Cardiology. ,vol. 11, pp. 69- 74 ,(2004) , 10.1097/01.HJR.0000114706.27531.01
Georgi Abraham, YuvaramN. V. Reddy, UlhasM Pandurangi, U Kalaichelvan, SBalashankar Gomathi, Milly Mathew, Roy Santhosham, Hariharan Iyer, Risk factors of chronic kidney disease influencing cardiac calcification. Saudi Journal of Kidney Diseases and Transplantation. ,vol. 24, pp. 1189- ,(2013) , 10.4103/1319-2442.121279
Rakesh K Sharma, Rajiv K Sharma, Donald J Voelker, Vibhuti N Singh, Deepak Pahuja, Teresa Nash, Hanumanth K Reddy, None, Cardiac risk stratification: role of the coronary calcium score. Vascular Health and Risk Management. ,vol. 6, pp. 603- 611 ,(2010) , 10.2147/VHRM.S8753
Udo Hoffmann, Joseph M. Massaro, Caroline S. Fox, Emily Manders, Christopher J. O'Donnell, Defining normal distributions of coronary artery calcium in women and men (from the Framingham Heart Study). American Journal of Cardiology. ,vol. 102, pp. 1136- 1141 ,(2008) , 10.1016/J.AMJCARD.2008.06.038
Abdelilah el Barzouhi, Suzette Elias-Smale, Abbas Dehghan, Rozemarijn Vliegenthart-Proença, Matthijs Oudkerk, Albert Hofman, Jacqueline C. M. Witteman, Renal Function Is Related to Severity of Coronary Artery Calcification in Elderly Persons: The Rotterdam Study PLoS ONE. ,vol. 6, pp. e16738- ,(2011) , 10.1371/JOURNAL.PONE.0016738
Jared P. Reis, Denise von Mühlen, Erin D. Michos, Edgar R. Miller, Lawrence J. Appel, Maria R. Araneta, Elizabeth Barrett-Connor, Serum vitamin D, parathyroid hormone levels, and carotid atherosclerosis. Atherosclerosis. ,vol. 207, pp. 585- 590 ,(2009) , 10.1016/J.ATHEROSCLEROSIS.2009.05.030
Catherine M. Loria, Kiang Liu, Cora E. Lewis, Stephen B. Hulley, Stephen Sidney, Pamela J. Schreiner, O. Dale Williams, Diane E. Bild, Robert Detrano, Early adult risk factor levels and subsequent coronary artery calcification: the CARDIA Study. Journal of the American College of Cardiology. ,vol. 49, pp. 2013- 2020 ,(2007) , 10.1016/J.JACC.2007.03.009
Caroline S. Fox, Martin G. Larson, Michelle J. Keyes, Daniel Levy, Melvin E. Clouse, Bruce Culleton, Christopher J. O'Donnell, Kidney function is inversely associated with coronary artery calcification in men and women free of cardiovascular disease: The Framingham Heart Study Kidney International. ,vol. 66, pp. 2017- 2021 ,(2004) , 10.1111/J.1523-1755.2004.00973.X