Bayesian estimation of cardiovascular autonomic neuropathy diagnostic test based on short-term heart rate variability without a gold standard

摘要: Objective To evaluate the reference values for short-term heart rate variability (HRV), estimate performance of cardiovascular autonomic neuropathy (CAN) diagnostic tests in absence a gold standard, and assess CAN prevalence our dataset. Setting Community hospital health centre. Participants Of 2092 subjects available data analysis, 371 healthy were selected so HRV test could be evaluated. An external dataset contained 88 who completed both Ewing9s test. Intervention Collection information on clinical outcome. Primary second outcome measures Cardiovascular function evaluated by using and/or Results Cut-off points 356.13, 55.45 36.64 ms 2 set total power, low frequency high (HF), respectively. The based mentioned value was created. had sensitivity (80.01–85.09%) specificity (82.30–85.20%) CAN. In addition, non-inferiority rejected null hypothesis that inferior to (p Conclusions Our findings provided HRV, which used with specificity. estimated Chinese population.