Body mass index interaction with SCN10A effects on cardiovascular autonomic neuropathy risk in a Chinese Han population
作者： Guo-Zhuo Wang , Zhi-Jun Liu , Kai Xia , Ke-Qin Zhang , Zi-Hui Tang
DOI: 10.1142/S2575900018500040
关键词:
摘要: Background: The aim of this study was to estimate the extent which interaction between SCN10A (rs7375096) and body mass index (BMI) affects susceptibility cardiovascular autonomic neuropathy (AN) in a Chinese Han sample. Method: We conducted large-scale, population-based including 791 overweight patients 1186 controls analyze BMI with regard CAN. All participants were genotyped for presence (rs7375036) polymorphisms. Univariate multiple linear regression analyses employed detect these relationships. rs7375036 CAN on an additive scale estimated by using relative excess risk due interaction, proportion attributable synergy index. Results: found no significant association single nucleotide polymorphism After controlling potential confounding factors, r...
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