Effects of axotomy, deafferentation, and reinnervation on sympathetic ganglionic synapses: a comparative study.

摘要: Abstract The main physiological and morphological features of the synapses in superior cervical ganglia mammals last two abdominal frog sympathetic chain are summarized. effects axotomy on structure function ganglionic then reviewed, as well various changes neuronal metabolism frog, which parallel between electrophysiological data leads to conclusion that a certain amount synaptic transmission occurs at “simple contacts.” deafferentation ultrastructure mammalian reviewed: most disappear, but number postsynaptic thickenings remain unchanged. Moreover, intrinsic persist after total their is strongly increased if added deafferentation. In ganglia, evolution areas comparable mammals, no observed. reinnervation deafferented by foreign nerves, motor or sensory, reported with different degrees efficiency. somatic nerve fibers obtained only 20% operated animals. possible reasons for high specificity connections discussed.