Seroprevalence study of Hantavirus infection in the community based population.

摘要: The genus Hantavirus, family Bunyaviridae, comprise at least 20 distinct viruses. Ten of these have been linked to specific human diseases. Hemorrhagic fever with renal syndrome has recognized since the 1950s. Hantavirus pulmonary was in United States 1993. Epizootiologic studies Norway rats Baltimore area shown that rodent infections hantaviruses are common and geographically widespread prevalence reaching 44% tested rat populations. These viruses antigenically related Seoul virus. humans occur through transmission from a reservoir, primarily by inhalation virus laden excreta. There is no evidence support person-to-person any known Hantavirus. To establish we collected sera 1,212 persons attending community based health care system. were for antibodies against three reference strains: Hantaan (HTN), (SEO), Convict Creek (HN017). HN017 chosen represent SinNombre (SN-like) strains Sera nine patients positive antibodies, HTN, SEO Enzyme Linked Imuno Sorbent Assay (ELISA). No antigen. All HTN western blot HTN. confirmed blot. This suggests unrecognized or Seoul-like humans, although rate low (0.74%). Epidemiologic monitoring may be warranted implications infections.