作者: R. Alan , B. Ezekowitz , S. Gordon
DOI: 10.1007/978-1-4757-1445-6_2
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摘要: The original definition of the activated macrophage described altered function these cells in antimicrobial activity and cell-mediated immunity (Mackaness, 1964), yet when role mammalian physiology pathology is considered it apparent that this may be too restricted. Inflammation, tissue remodeling, degradation, turnover normal body constituents antitumor resistance could more general expressions enhanced functions. With different roles mind, necessary to consider properties distinguish acquired states activation from nonactivated or resident state.