Predictive risk factors for lymph node metastasis in patients with small size non-small cell lung cancer
作者： Ping Yuan , Xiaoshuai Yuan , Feichao Bao , Zhitian Wang , Xiayi Lv
DOI: 10.3978/J.ISSN.2072-1439.2014.11.05
关键词:
摘要: Background: Accurate clinical staging of non-small cell lung cancer (NSCLC) is essential for developing an optimal treatment strategy. This study aimed to determine the predictive risk factors lymph node metastasis, including both N1 and N2 metastases, in T1aN0 NSCLC patients. Methods: We retrospectively evaluated T1aN0M0 patients who showed no radiologic evidence had undergone surgical pulmonary resection with systematic mediastinal dissection or sampling at First Affiliated Hospital Zhejiang University between January 2011 June 2013. Univariate multivariate logistic regression analyses were performed identify metastasis. Results: Pathologically positive nodes found 16.2% (51/315) Positive 12.4% (39/315) patients, identified 13.0% (41/315) Some 9.2% (29/315) nodes, 3.8% (12/315) nodal skip Variables preoperative radiographic tumor size, nonupper lobe located tumors, high carcinoembryonic antigen (CEA) levels micropapillary predominant adenocarcinoma (AC) as predictors analysis. Conclusions: common small size negative nodes. Therefore, should be more thoroughly increase accuracy, especially have larger non-upper located, CEA level ACs.
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