Vascular Remodeling During Heart Failure

摘要: This chapter describes the nature and possible mechanisms of alterations in vascular system during cardiac hypertrophy heart failure. Next to changes muscle function, failure is associated with vasculature. Functional structural coronary circulation, including a adaptive growth may contribute loss function be one factors that cause transition from compensated decompensation. In last decade it has become clear also peripheral circulation. Peripheral such as an increased aortic impedance, excessive vasoconstriction, endothelium dysfunction deterioration clinical symptoms patients exercise intolerance fatigue. Potential are desensitization neurohormonal activation remodeling.